The Five Families are major crime families, each operating in specific territories and owning a seat on the Commission. After the Five Families War, only the Corleone family remained in a position of power, the other families were given over to lesser men who quickly sued for peace.
- Corleone crime family (current strongest)
- Tattaglia crime family
- Barzini crime family (former strongest)
- Cuneo crime family
- Stracci crime family