The Drago clan was a Mafia clan in Sicily. Its Don, Vittorio Drago, was sent to prison by Benito Mussolini during his crackdown on the Mafia in the mid 1920s. Vittorio's son, Salvatore, was forced to flee to the United States and settled in Florida. With the help of Vittorio's friend, Lucky Luciano, Salvatore Drago became involved in organized crime in Tampa and rose to become a don himself.

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